Ingolia NT, Weissman JS. (2008) Systems biology: Reverse engineering the cell. Nature; 454:1059-62.

Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell; 134:634-45.

Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. (2008) High-throughput, quantitative analyses of genetic interactions in E. coli. Nat Methods; Aug 1. [Epub ahead of print]

Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods; 8:711-8.

McDonald M, Kendall A, Tanaka M, Weissman JS, Stubbs G. (2008) Enclosed chambers for humidity control and sample containment in fiber diffraction. J Appl Cryst, 41:206-209.

Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. (2007) Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A 104:18079-84.

Roguev A, Wiren M, Weissman JS, Krogan NJ. High-throughput genetic interaction mapping in the fission yeast Schizosaccaromyces pombe. Nat Methods; 10:861-866.

Morrison AJ, Kim J-A, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. (2007) Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell; 130:499-511.

Denic V, Weissman JS. (2007) A molecular caliper mechanism for determining very long-chain fatty acid length. Cell; Aug 24;130(4):663-77

Toyama BH, Kelly MJS, Gross JD, Weissman JS. (2007) The structural basis of yeast prion strain variants. Nature; 449: 233-7.

Laribee NR, Yoichiro S, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman J, Briggs SD, Krogan NJ, Strahl BD. (2007) CCR4/NOT complex associates with the proteasome and regulates histone methylation. PNAS USA; 104:5836-41.

Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, Andrews B, Boone C, Berger SL, Hieter P, Zhang Z, Brown GW, Ingles CJ, Emili A, Allis CD, Toczyski DP, *Weissman JS, *Greenblatt JF, Krogan NJ. (2007) Functional dissection of yeast chromosome biology complexes using a genetic interaction map. Nature; 446:806-810. *corresponding authors

Ihmels J, Collins S, Schuldiner M, Krogan N, Weissman J. (2007) Genetic interactions reveal the cost of gene loss for singleton and duplicate genes. Mol Sys Biol; 3:86.

Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. (2007) Towards a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics; 6:439-50.

Schuldiner M, Collins SR, Weissman JS, Krogan NJ. (2006) Quantitative genetic analysis in S. cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods; 40:344-52.

Newman JR, Weissman JS. (2006) Systems Biology: many things from one. Nature; 444:561-2.

Tanaka M, Collins SR, Toyama BH, Weissman JS. (2006) The physical basis of how prion conformations determine strain phenotypes. Nature; 442:585-9.

Denic V, Quan EM, Weissman JS. (2006) A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell; 126:349-59.

Hollien J, Weissman JS. (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science; 313:104-7.

Collins SR, Schuldiner MB, Krogan NJ, Weissman JS. (2006) A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biol; 7:R63.

Newman JRS, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. (2006) Single-cell proteomics of the budding yeast saccharomyces cerevisiae. Nature; 144:840-846.

Bukau B, Weissman J, Horwich A. (2006) Molecular chaperones and protein quality control. Cell; 125:3.

Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrin-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF. (2006) Global landscape of protein complexes in the yeast saccharomyces cerevisiae. Nature; 440:7084.

Kulp MS, Frickel EM, Ellgaard L, Weissman JS. (2006) Domain architecture of protein disulfide isomerase facilitates its dual role as an oxidase and an isomerase in ERO1P-mediated disulfide formation. J Biol Chem; 281:876-884.

Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ. (2005) Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell; 123:4.

Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, *Weissman JS, Krogan NJ. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell; 123:366-8. *corresponding author

Bhamidipati A, Denic V, Quan EM, Weissman JS. (2005) Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol Cell; 19:1-11.

Tanaka M, Chien P, Yonekura K, Weissman JS. (2005) Mechanism of cross-species prion transmission: An infectious conformation compatible with two highly divergent yeast prion proteins. Cell; 121:49-62.

Howson R, Huh W, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, OShea EK. (2005) Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains (p 2-16). Comp Funct Genom 2004; 5:000�000.

Tu BP, Weissman JS. (2004) Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol; 164:341-346.

Weissman JS, OShea EK. (2004) Irving Sigal Young Investigator Award Address. Protein Sci; 13:3333-3335.

Collins SR, Douglass A, Vale RD, Weissman JS. (2004) Mechanism of prion propagation: Amyloid growth occurs by monomer addition. PloS Biol; 2:1499-1500.

Osherovich LZ, Cox BS, Tuite MF, Weissman JS. (2004) Dissection and design of yeast prions. PloS Biol; 2:0442-0451

Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. (2004) Conformational variations in an infectious protein determine prion strain differences. Nature; 428:323-28.

Chien P, Weissman JS, DePace AH. (2004) Emerging principles of conformation-based prion inheritance. Annu Rev Biochem; 73:617-56.

Ghaemmaghami S, Huh W-K, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. (2003) Global analysis of protein expression in yeast. Nature; 425:737-41.

Huh W-K, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. (2003) Global analysis of protein localization in budding yeast. Nature; 425:686-91.

Chien P, DePace AH, Collins S, Weissman JS. (2003) Generation of prion transmission barriers by mutational control of amyloid conformations. Nature; 424:948-51.

Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. (2002) Directed evolution of substrate-optimized GroEL/S chaperonins. Cell; 111:1027-1039.

Tu BP, Weissman JS. (2002) The FAD- and O2-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol Cell; 10:983-994.

DePace AH, Weissman JS. (2002) Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nat Struct Biol; 9:389-395.

Osherovich LZ, Weissman JS. (2002) The utility of prions. Dev Cell; 2:143-152.

Weissman JS, Hood JK. (2001) Prion diseases. A rogue protein. Lancet; 358:s53.

Weissman JS. (2001) The ins and outs of GroEL-mediated folding. Mol Cell; 8:730-732.

Travers KT, Patil CP, Weissman JS. (2001) Functional genomic approaches to understanding molecular chaperones and stress responses. Adv Protein Chem; 59:345-390.

Fewell SW, Travers KT, Weissman JS, Brodsky JL. (2001) The action of molecular chaperones in the early secretory pathway. Annu Rev Genet; 35:149-91.

Osherovich LZ, Weissman JS. (2001) Multiple Gln/Asn-Rich prion domains confer susceptibility to induction of the yeast [PSI+] prion. Cell; 106:183-194.

Chien PC, Weissman JS. (2001) Conformational diversity in a yeast prion dictates its seeding specificity. Nature; 410:223-227.

Tu BP, Ho-Scheleyer SC, Travers KJ, Weissman JS. (2000) Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science; 290:1571-1574.

Michelitsch MD, Weissman JS. (2000) A census of glutamine/asparagine-rich regions: Implications for their conserved function and the prediction of novel prions. Proc Natl Acad Sci USA; 97:11910-11915.

Sparrer HE, Santoso A, Szoka Jr FC, Weissman JS. (2000) Evidence for the prion hypothesis: Induction of the yeast [PSI+] factor by in vitro-converted Sup35 protein. Science; 289:595-599.

Travers KT, Patil CP, Wodicka L, Lockhart DJ, Weissman JS, Walter P. (2000) Functional and genomic analyses reveal essential coordination between the unfolded protein response and ER-associated degradation. Cell; 101:249-258.

Santoso A, Chien P, Weissman JS. (2000) Molecular basis of a yeast prion species barrier. Cell; 100:277-288.

Wang JD, Weissman JS. (1999) Thinking outside the box: new insights into the mechanism of GroEL-mediated folding. Nat Struct Biol; 6:597-600.

DePace AH, Santoso A, Hillner P, Weissman JS. (1998) A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell; 93:1241-1252.

Wang JD, Michelitsch MD, Weissman JS. (1998) GroEL-GroES-mediated protein folding requires an intact central cavity. Proc Natl Acad Sci USA; 95:12163-12168.

Horwich AL, Burston SG, Rye HS, Weissman JS, Fenton WA. (1998) Construction of single-ring and two-ring hybrid versions of bacterial chaperonin GroEL. Methods Enzymol; 290:141-146.

Pollard M, Travers KT, Weissman JS. (1998) Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Mol Cell; 1:171-182.

Horwich AL, Weissman JS. (1997) Deadly conformations--protein misfolding in prion disease. Cell; 89:499-510.

Fenton WA, Weissman JS, Horwich AL. (1996) Putting a lid on protein folding: structure and function of GroES. Chem Biol; 3:157-161.